Differential Oligomerization of Endoplasmic Reticulum-Retained Connexin43/Connexin32 Chimeras
نویسندگان
چکیده
منابع مشابه
Mutant prion proteins are partially retained in the endoplasmic reticulum.
Familial prion diseases are linked to point and insertional mutations in the prion protein (PrP) gene that are presumed to favor conversion of the cellular isoform of PrP to the infectious isoform. In this report, we have investigated the subcellular localization of PrP molecules carrying pathogenic mutations using immunofluorescence staining, immunogold labeling, and PrP-green fluorescent prot...
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Tapasin retains empty or suboptimally loaded MHC class I molecules in the endoplasmic reticulum (ER). However, the molecular mechanism of this process and how tapasin itself is retained in the ER are unknown. These questions were addressed by tagging tapasin with the cyan fluorescent protein or yellow fluorescent protein (YFP) and probing the distribution and mobility of the tagged proteins. YF...
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ژورنال
عنوان ژورنال: Cell Communication & Adhesion
سال: 2003
ISSN: 1541-9061,1543-5180
DOI: 10.1080/cac.10.4-6.319.322